The Unrivaled Grand Tourer: A Deep Dive into the 2025 Mercedes-Benz GLS 580 4Matic
As we navigate the automotive landscape of 2025, a particular segment continues to captivate discerning buyers: the full-size luxury SUV. These vehicles are no longer merely about transporting families; they represent a pinnacle of engineering, comfort, and advanced technology. Among the contenders, the 2025 Mercedes-Benz GLS 580 4Matic stands out as a true titan, a vehicle meticulously crafted not just for utility, but for an unparalleled experience on the open road. Having spent countless hours behind the wheel of various high-end SUVs over the past decade, I can attest that the GLS 580 isn’t just a mode of transport; it’s a statement, an sanctuary, and a formidable powerhouse all rolled into one.
The drive from Milwaukee to St. Louis, a journey often characterized by its seemingly endless stretches of highway and a landscape dominated by agricultural expanse, serves as an ideal proving ground for any long-distance cruiser. It’s six hours where the quality of your vehicle truly matters. During such journeys, the priorities shift from mere speed to a sublime blend of smoothness, spaciousness, and passenger comfort,
amplified by a powerful yet refined engine. It’s in this demanding scenario that the 2025 Mercedes-Benz GLS 580 4Matic doesn’t just perform; it excels, redefining what a luxury family SUV can achieve.
This vehicle is a masterclass in versatility. It seamlessly integrates state-of-the-art technology and opulent luxury for a serene cruising experience, yet never sacrifices capability. Beneath its elegantly sculpted hood lies robust power, complemented by a cavernous cabin designed to comfortably accommodate up to seven passengers. Furthermore, its impressive towing capacity and even a surprising degree of off-road prowess underscore its multifaceted nature. This breadth of capability is vital, especially when considering its premium positioning, with a starting MSRP of $115,950, inclusive of a $1,150 destination charge. Our comprehensively optioned road-trip companion, for instance, commanded a price tag of $126,610, a testament to the extensive array of Mercedes-Benz advanced features available to elevate the ownership experience.
Engineered for Excellence: Powertrain and Performance
The heart of the GLS 580 4Matic is undoubtedly its powertrain – a masterpiece of modern automotive engineering. Mercedes-Benz’s renowned twin-turbocharged 4.0-liter V8 engine, an icon of performance and refinement, is housed under that distinctive domed and ridged hood. In this iteration, it delivers a formidable 510 horsepower and 538 pound-feet of torque. What truly sets it apart, however, is the seamless integration of a 48-volt mild-hybrid system. This intelligent system doesn’t just enhance efficiency; it can contribute an additional 21 horsepower and a substantial 184 pound-feet of torque during initial acceleration and low-speed maneuvers, providing an instantaneous, silken surge of power that belies the vehicle’s considerable mass.
During extensive highway stretches, a real-time power meter often displayed consumption figures around 30 horsepower and 150 pound-feet of torque, highlighting the engine’s effortless efficiency at cruise. However, the moment an opportunity arose to overtake slower traffic, the robust thrust of the V8 was immediately accessible. The nine-speed automatic transmission, a paragon of smooth shifts and rapid kick-downs, works in perfect harmony with the engine. A deep, authoritative bellow from the V8 accompanies the swift acceleration of this nearly 5,875-pound German high-performance SUV, allowing it to effortlessly fill gaps in traffic. From a standstill, the GLS 580 is surprisingly agile, capable of rocketing from 0-60 mph in a brisk 4.7 seconds, a figure that rivals many dedicated sports cars, let alone a three-row luxury behemoth.
Power distribution is handled with sophisticated precision by Mercedes’ proprietary 4Matic all-wheel-drive system. This intelligent system continuously monitors traction and can proactively distribute torque between the front and rear axles to maximize grip and stability, whether on dry pavement, slick roads, or light off-road terrain. The inherent strength of the V8, combined with the robust nine-speed transmission and a meticulously engineered unibody structure, endows the GLS 580 with an impressive towing capacity of up to 7,716 pounds. This substantial figure makes it an ideal choice for owners needing to haul a significant boat, a multi-horse trailer, or other substantial recreational equipment, positioning it as a truly versatile executive SUV.
Ride, Handling, and Off-Road Prowess
Beyond raw power, the driving experience in a luxury SUV is largely defined by its ride and handling characteristics. The GLS 580 excels here, albeit with nuances. Standard air suspension, paired with adaptive dampers, ensures an inherently smooth ride across varied road surfaces. This system dynamically adjusts damping forces at each wheel, absorbing bumps and imperfections before they can disturb the cabin. With a standard ground clearance of 7.9 inches, the GLS maintains a commanding presence.
However, in the default “Comfort” drive mode, the immense size and elevated stance can sometimes translate into a sensation of being slightly top-heavy. Minor road undulations or quick steering inputs might induce a subtle “head toss” for passengers. As an experienced driver, I found that selecting the “Sport” handling setting within the “Individual” drive mode significantly transforms the vehicle’s dynamic behavior. This adjustment firms up the suspension, noticeably reducing body lean in corners and making the GLS feel considerably more composed and “buttoned down.” It’s a subtle but impactful change that enhances stability and driver confidence, particularly when navigating winding roads or during higher-speed maneuvers.
The “Individual” mode further allows for personalized adjustments to steering feel and stability control. While the GLS is not designed to be thrown around corners like a smaller sports sedan – its considerable mass and generous dimensions would preclude truly playful dynamics – the unibody construction provides a distinct advantage over traditional body-on-frame competitors like the Cadillac Escalade or Lincoln Navigator. This integrated body structure contributes to a lighter feel, a smoother ride, and superior body control, offering a more refined and car-like driving experience.
While its primary habitat is the paved road, the GLS 580 surprises with a respectable degree of off-road capability. This largely stems from its sophisticated air suspension, which, when engaged in “Off-road” mode, can elevate the ground clearance by a couple of inches. This extra lift is invaluable for clearing modest obstacles on unpaved trails or navigating uneven terrain. Complementing this, Mercedes-Benz offers an intuitive “Off-road Cockpit” screen within the MBUX infotainment system. This display provides crucial real-time data, including individual wheel height, tire pressure and temperature, and steering angle. Revolutionary “transparent hood” and forward-view cameras offer drivers an unobstructed virtual view of what’s directly ahead of and even underneath the vehicle, making precise wheel placement on challenging paths significantly easier. It’s important to note, however, that the standard 285/45R22 front and 325/40R22 rear Continental EcoContact6 Q MO tires, while exceptional for ride quality and highway quietness, are optimized for road use rather than aggressive off-road traction. For true off-road enthusiasts, an alternative tire package would be a wise consideration.
The trade-off for such prodigious power, capability, and sheer size is, predictably, fuel economy. The EPA rates the GLS 580 at 14 mpg city, 19 mpg highway, and 16 mpg combined. Impressively, during my extensive 950-mile road trip, I managed to slightly exceed these figures, averaging a commendable 19.4 mpg. This is a testament to the efficiency of the mild-hybrid system and the V8’s ability to operate efficiently at cruising speeds.
An Interior Sanctuary: Luxury, Technology, and Comfort
Stepping into the cabin of the 2025 Mercedes-Benz GLS 580 4Matic is akin to entering a meticulously crafted, serene sanctuary. The interior design language effortlessly blends modern aesthetics with timeless elegance, utilizing premium materials throughout. From the driver’s perspective, every element is designed to enhance comfort and provide access to cutting-edge technology, making it the quintessential long-distance comfort SUV.
The multi-contour front seats are a highlight, offering exceptional support for long journeys, and are further enhanced by standard head pillows that cradle the neck and head. The inclusion of standard massaging seats takes comfort to another level, providing a spa-like experience on the go. While I personally found both features incredibly beneficial, offering relief and relaxation during extended drives, it’s a curious quirk of human preference that my lifelong best friend found them somewhat intrusive. It simply underscores that luxury, like taste, is deeply personal.
At the heart of the digital cockpit are two brilliant 12.3-inch screens. The central infotainment touchscreen, running the latest iteration of Mercedes’ MBUX (Mercedes-Benz User Experience) software, is arguably among the industry’s best. Its responsiveness is immediate, and navigating between functions such such as satellite radio, Apple CarPlay, or the integrated navigation system is intuitive and seamless. Beyond touch, the system can be controlled via steering wheel-mounted touch controls or a sleek trackpad on the center console. While the trackpad offers an alternative input method, its placement does consume valuable real estate that could potentially be utilized for additional storage. The second 12.3-inch digital instrument cluster is highly customizable, allowing drivers to display a wealth of essential information tailored to their preferences, cycling through four distinct display themes.
In the realm of premium SUV technology, driver-assist systems are paramount. The GLS 580 comes equipped with robust adaptive cruise control and lane-keep assist systems. These effectively maintain a set distance from the vehicle ahead and help keep the SUV centered within its lane. However, unlike some competitors or Mercedes’ own Level 3 “Drive Pilot” system available in the S-Class and EQS (currently limited to specific Western states), these systems still require the driver to keep their hands on the steering wheel. While highly effective in reducing driver fatigue on monotonous stretches, the absence of a truly hands-free experience is a notable point in a vehicle of this caliber in 2025. It certainly left me wishing for that extra layer of autonomy during those long, straight stretches.
Passenger Accommodations and Versatility
The GLS 580 is designed to accommodate. During my travels, I comfortably hosted up to five passengers, and the vehicle handled the full complement with grace. With the third row folded flat – a process effortlessly managed via power controls – the cargo hold easily swallowed three gym bags and two coolers, demonstrating its excellent utility. While the cargo capacity behind the third row is a modest 17.4 cubic feet, it rapidly expands to a cavernous and highly functional 84.7 cubic feet with both the second and third rows folded flat, making it supremely practical for hauling larger items or extensive luggage for extended trips. This adaptability firmly solidifies its position as a class-leading luxury car features loaded family hauler.
Passenger space is truly a strong suit. The second-row captain’s chairs, a favored option, provide individual bucket-seat comfort, offering more than ample space for adult passengers. These seats are heated, and second-row occupants enjoy independent control over their dual-zone climate settings via a dedicated small display screen with tactile hard buttons, further enhancing their comfort and convenience.
Even the third row, often an afterthought in many SUVs, is surprisingly accommodating. It comfortably seats two adults and boasts its own dedicated climate zone. The bottom cushion is positioned high enough to provide good thigh support, and headroom is sufficient even for a six-footer. Legroom, however, can become a consideration if exceptionally tall individuals occupy all three rows simultaneously.
My passengers, while generally effusive in their praise, did offer a few constructive observations. A common sentiment was that the running boards, while aesthetically integrated, were tucked in too tightly to the body to offer practical assistance for ingress and egress. Another minor gripe was the wish for both second-row seats to tilt and slide forward for third-row access; currently, only the passenger-side seat offers this functionality. And, of course, the general complaint about the monotonous Midwestern landscape, coupled with the aforementioned individual preference regarding massaging seats and head pillows, merely underscores that even in a vehicle as sublime as the GLS 580, personal tastes and external circumstances always play a role!
The Verdict: A Benchmark in Luxury and Performance
The 2025 Mercedes-Benz GLS 580 4Matic is more than just a large SUV; it’s a testament to what happens when uncompromising luxury meets formidable performance and exceptional versatility. It stands as a compelling choice for those who demand the absolute best in every aspect of their driving experience. From its potent and refined mild-hybrid V8 engine, delivering exhilarating high-end SUV performance, to its sumptuously appointed interior brimming with premium SUV technology, the GLS 580 delivers on every promise.
It effortlessly devours monotonous miles, transforming tedious journeys into remarkably comfortable and enjoyable experiences. Its robust all-wheel-drive SUV capability ensures confidence regardless of weather conditions, and its substantial towing capacity expands its utility significantly. While its price point places it firmly in the upper echelon of the market, the sheer breadth of its abilities, the depth of its luxury, and the advanced engineering within its Mercedes-Benz powertrain justify the investment for discerning buyers.
In the rapidly evolving world of 2025, where the lines between luxury, technology, and performance continue to blur, the GLS 580 4Matic not only keeps pace but often sets the standard. It provides a holistic premium automotive experience that few can match, solidifying its reputation as a leading contender for the title of best luxury SUV 2025 has to offer. For families seeking an uncompromising blend of comfort, power, and prestige for their adventures, the 2025 Mercedes-Benz GLS 580 4Matic is an intelligent and immensely satisfying choice.

